Dele Alli, Toby Alderweireld and Erik Lamela struck in six second-half minutes as Tottenham Hotspur swamped Manchester United 3-0 on Sunday to keep their title hopes alive seven points behind league leaders Leicester City.
Kick-off was delayed by half an hour as the visitors’ team bus fell foul of London traffic and the match started slowly, as White Hart Lane endured a first half without a shot on target.
But 0-0 became 3-0 within six scintillating second-half minutes as Dele Alli, Toby Alderweireld and Erik Lamela struck to land blows to Man Utd's hopes of a top-four finish.
Pochettino had not beaten United in six previous attempts, first with Southampton and then Tottenham, and Spurs had not scored against them in three games under him. Both trends were reversed in stunning fashion.
The result, Spurs' first home league win over United in 15 years, had the additional effect of securing Leicester's place in the Champions League and United's hopes of joining the Foxes at Europe's top table are fading.
Elsewhere Leicester City secured a Champions League place for the first time in their history after beating Sunderland 2-0.
The results means Claudio Ranieri's side, who currently have 72 points after 33 games, cannot finish lower than fourth in the Premier League this season, with just five games left to play.
The Foxes remain hot favorites to finish this season as champions after two goals from Jamie Vardy saw them down Sunderland at the Stadium of Light.